Are there different types of thrombosis?

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Thrombosis may be arterial or venous. Venous thromboembolic disease (ETV) They are the third cause of death after cardiovascular ischemic heart disease and stroke.

The blood, from the beginning of time, It has been associated with a substantial value. Many people are impressed only see it and imagine it all as a symbol of life. The art uses it in all its manifestations. Its emblematic color highlights its vitality.

In the meantime, blood flows through veins and arteries, nourishing the body of living beings, who have a system that normally holds the balance.

Sometimes, it is interrupted; and this happens, as well, in the blood., consulted biochemistry, Specialist in Hematology, Sandra Noemi Suarez, who, among other concepts, He answers the question “What is meant by hemostasis?”, stating that “It is the process that maintains the integrity of the vascular system after damage or injury occurred. This integrity is maintained by a complex but carefully controlled system which requires interaction between the vessel wall (endothelium), platelets, coagulation factors and fibrinolytic system ".

What is its purpose?

Limit blood loss, preserve tissue perfusion and stimulate local repair processes. When a pathological process alters the mechanisms of regulation of hemostasis, the balance is lost between the procoagulant and anticoagulant system, which may cause bleeding or conversely, excessive coagulation activation or inhibition of anticoagulant mechanisms leading to a hypercoagulable state and development of thrombosis.

Are there different types of thrombosis?

Thrombosis may be arterial or venous. Venous thromboembolic disease (ETV) They are the third cause of death after cardiovascular ischemic heart disease and stroke.

How can we understand what is thrombophilia?

It is the predisposition to blood clots (is not a disease per se), which causes high morbidity and mortality, so it has become a serious health problem worldwide. This condition may be primary (hereditary) or secondary (acquired) when it associated with acquired risk factors. Primary thrombophilia is associated with hereditary factors that favor a hypercoagulable state. This is suspected in patients under 50 years with thrombotic episode, without the presence of secondary factors associated. Acquired thrombophilia is associated with autoimmune diseases, Cancer, surgical procedures, pregnancy, puerperium, obesity, oral contraceptives, etc.. Acquired thrombophilias, antiphospholipid syndrome (PURE) It is the most frequent cause.

It is characterized by clinical manifestations associated with thrombotic events, pregnancy morbidity, recurrent fetal loss and persistent presence of antiphospholipid antibodies (AFL). Often associated with other pathologies, primarily SLE (THE), or other autoimmune diseases.

Are there specific analysis and specialized laboratories for thrombophilia?

Currently, with the addition of new analytical methods, hemostasis laboratory has tools to analyze the causes of thrombophilic state, collaborating with the choice of appropriate treatment in each particular case.

Can you list the causes of thrombophilia?

To date they have been recognized as the leading causes of inherited thrombophilia: deficiencies natural anticoagulant proteins such as antithrombin, Protein C and protein S, and the presence of mutations as: Factor V Leiden and G20210A A prothrombin gene (PG20210A), the latter assayed by DNA analysis.

* Screening for thrombophilia study is not indicated for routine, but it may be considered when two or more risk factors are identified, including age of presentation prior thrombotic event highlighted the 50 years old, TVP (DVT) recurrent and unusual sites, family history of thrombosis, obstetric complications early or late, or pregnancy losses.

Laboratory evaluation should always be requested by the specialist physician based on clinical criteria.

*Screening, in medicine, is an anglicized used to indicate applied to a population for disease in individuals without signs or symptoms of that disease strategy. The intent of screening is to identify disease early within a community.}

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